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Fig. 3 | Cancer & Metabolism

Fig. 3

From: Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer

Fig. 3

PEPCKi decreases proliferation in colorectal cancer cells. af Colo205, Ls180, Ls174T, HT29, SW180, and HCT116 cells, respectively, were treated with PEPCKi and cell number determined. g HT29 cells stably expressing an empty vector or PEPCK were treated with indicated doses of PEPCKi and cell number determined. h Colo205 cells with shNT or shPEPCK were treated 10 μM PEPCKi and cell number determined. Cells were seeded and treated with indicated doses of inhibitor for up to 5 days. N = 3 ± SD. *p < 0.05, **p < 0.01

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