Fig. 3From: Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallateEGCG inhibits the activity of IDH1 and GLUD1/2. IDH1 (a) and GLUD1/2 (b) activities were inhibited by EGCG, but this effect was much more pronounced in GLUD1/2. Activity was determined by measuring NADP(H)-generated absorption at 340 nm. Activity was corrected for absorption measured with cofactors, without the addition of enzymeBack to article page