Fig. 2From: Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHCSDHC gene expression in subgroups of breast cancer. The two cohorts included in the study was subdivided based on molecular characteristics such as estrogen receptor positive and negative (ER+ and ER−) and basal- and non-basal phenotype. Claudin-low and triple negative subgroups were included in the basal category. In addition, the breast cancer patient cohort (n = 204) was subgrouped based on histology, i.e., into ducal and lobular characteristics. a mRNA expression of SDHC and b EMT8 signature were assessed for the distinct subgroups in the n = 204 cohort. c mRNA expression of SDHC and d EMT8 and EMT315 signatures were determined for the subgroups in the n = 3992 Affymetrix meta cohort. e Spearman correlation analysis for SDHC expression relative to EMT8 signature for subgroups of the breast cancer cohort (n = 204) and f the Affymetrix meta cohort. g Kaplan-Meier survival plots for basal- (n = 42) and non-basal-like (n = 161) breast carcinoma of the breast cancer cohort. The gene expression data are displayed with relative arbitrary unitsBack to article page