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Fig. 6 | Cancer & Metabolism

Fig. 6

From: Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9)

Fig. 6

Schematic illustration. a Table summarizes levels of LDLc and PCSK9 in serum, LDLR and PCSK9 protein in liver and tumor tissues of mice from group II and group IV when compared with group I and group III respectively. NA denotes not applicable, and the number sign denotes non-significant change. b The proposed model demonstrate HG-driven changes in HepG2 tumor leading to increased expression of PCSK9 and associated hypercholesrolemia which can further lead to HCC cell survival by decreasing the efficacy of sorafenib

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