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Fig. 2 | Cancer & Metabolism

Fig. 2

From: Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9)

Fig. 2

Glucose feeding differentially alters hepatic PCSK9 and LDLR protein level in presence and absence of HepG2-tumors. a Low-density lipoprotein cholesterol (mg/dl), total cholesterol (mg/dl), and triglycerides (mg/dl) in serum samples were estimated using kits as per the manufacturer’s instructions. b Mouse liver homogenates from groups I and II (left panel) and groups III and IV (right panel) were resolved by SDS-PAGE, LDLR and PCSK9 levels were analyzed by Western blot. Band intensities were measured by densitometry and normalized with β-actin. The results are given as means ± standard deviation; *p < 0.05 denote significant differences in the groups; ns non-significant

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