Fig. 1From: Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcomaHuman and mouse soft tissue sarcomas express PKM2. Representative images of IHC for PKM1 and PKM2 in human (a) and mouse (b) skeletal muscle and human rhabdomyosarcoma (c). Corresponding H&E images are shown. Scale bars, 20 μm. d Quantification of PKM1 and PKM2 staining intensities in human rhabdomyosarcoma tumors relative to rhabdomyosarcoma subtype (embryonal, spindle cells, alveolus, pleomorphic). Score 0 = no staining, score 1 = weak, score 2 = positive, or score 3 = strongBack to article page