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Fig. 4 | Cancer & Metabolism

Fig. 4

From: Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner

Fig. 4

HIF-1α downregulates PC and PE synthesis in IDHmut glioma cells. a Representative western blot showing the effect of 2-HG on HIF-1α in the NHA model. b Representative western blots showing silencing of HIF-1α in the NHA model. Effect of HIF-1α silencing on PC (c), PE (d), CKα expression (e), CK activity (f), and EK activity (g) in the NHA model

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Cancer & Metabolism

ISSN: 2049-3002