Fig. 7

IDH1 mutant enzyme leads to higher ROS levels. a Histogram displaying ROS levels of three IDH1 mutant and three IDH1 wildtype gliomaspheres measured using flow cytometry (CellROX Green). b Similar ROS analysis of an IDH WT line (HK308) with and without IDH1 mutant overexpression (CellROX Deep Red). Results shown are from individual experiments. Three replicates yielded identical findings