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Table 1 Genetic differences between CCRF CEM and MDA MB231 cell lines

From: Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA

Gene expression Peripheral blood (acute lymphoblastic) Breast (adenocarcinoma)
CCRF CEM MDA MB 231
NAMPT Intermediate High
NAPRT High
QPRT High Very low
NRK Low Intermediate
LDH Intermediate Intermediate
PTEN* Mutation
KRAS* Mutation Mutation
TP53* Mutation
BRAF* Mutation
CDKN2A* Mutation
  1. *Source: ATCC cell lines by gene mutation