Skip to main content

Table 1 List of metabolites significantly changed in metastasis tissues (n = 4) compared to primary tumor tissues (n = 4), paired Welch’s t test

From: Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids

Metabolite name

Mass-to-charge ratio [M-H]

Fold change

Retention time (min)

Direction of change in metastasis

p value

Cholesterol sulfate

465.3050

5.7

15.59

4.00E−04

16:0 Lyso phosphatidylethanolamine

452.2771

3.0

16.67

1.86E−03

DPPG (16:0 phosphatidylglycerol)

721.5012

15.2

17.11

2.80E−03

POPG (16:0/18:1 phosphatidylglycerol)

747.5185

2.5

17.03

1.41E−02

16:0 Lyso phosphatidylglycerol

483.2719

14.0

18.66

1.68E−02

Cytidine monophosphate

322.0443

4.3

36.70

9.20E−04

Citrate/isocitrate

191.0202

2.8

42.79

1.20E−03

Guanosine monophosphate

362.0505

2.2

39.84

1.24E−03

Uridine monophosphate

323.0286

3.8

36.96

2.40E−03

N6-succinyl adenosine

382.0999

7.0

36.42

4.44E−03

Glutamine

145.0621

1.8

21.63

6.14E−03

N-acetyl-l-glutamate

188.0565

6.5

34.66

4.32E−02

Adenosine monophosphate

346.0560

2.0

37.23

4.92E−02

Uridine 5′-diphosphoglucuronate

579.0262

2.1

42.95

4.99E−02