Table 1 Significantly regulated proteins in response to PHD3 silencing according to PECA analysis under normoxia
Accession | Protein name | Gene name | Log2 fold change | FDR |
|---|---|---|---|---|
Upregulated | ||||
 P09493 | Tropomyosin alpha-1 chain | TPM1 C15orf13 TMSA | 1.5144 | 0.0260 |
 P31943 | Heterogeneous nuclear ribonucleoprotein H | HNRNPH1 HNRPH HNRPH1 | 1.3557 | 0.0020 |
 P35527 | Keratin, type I cytoskeletal 9 | KRT9 | 1.0655 | 0.0124 |
 Q15436 | Protein transport protein Sec23A | SEC23A | 0.9224 | 0.0092 |
 P09429 | High mobility group protein B1 | HMGB1 HMG1 | 0.8762 | 0.0000 |
 P51148 | Ras-related protein Rab-5C | RAB5C RABL | 0.7977 | 0.0016 |
 O43852 | Calumenin | CALU | 0.6639 | 0.0007 |
 P38646 | Stress-70 protein, mitochondrial | HSPA9 GRP75 HSPA9B mt-HSP70 | 0.6142 | 0.0000 |
 O75874 | Isocitrate dehydrogenase | IDH1 PICD | 0.5916 | 0.0116 |
 O43707 | Alpha-actinin-4 | ACTN4 | 0.4702 | 0.0008 |
 Q06210 | Glutamine—fructose-6-phosphate aminotransferase | GFPT1 GFAT GFPT | 0.4654 | 0.0449 |
 P07195 | l-lactate dehydrogenase B chain | LDHB | 0.4116 | 0.0020 |
 P55072 | Transitional endoplasmic reticulum ATPase | VCP | 0.3889 | 0.0002 |
 P11413 | Glucose-6-phosphate 1-dehydrogenase | G6PD | 0.3781 | 0.0116 |
Downregulated | ||||
 P31939 | Bifunctional purine biosynthesis protein PURH | ATIC PURH OK/SW-cl.86 | −1.6058 | 0.0116 |
 Q92597 | Protein NDRG1 | NDRG1 CAP43 DRG1 RTP | −1.3053 | 0.0000 |
 O15460 | Prolyl 4-hydroxylase subunit alpha-2 | P4HA2 UNQ290/PRO330 | −1.1904 | 0.0000 |
 O43776 | Asparagine—tRNA ligase, cytoplasmic | NARS | −0.9285 | 0.0000 |
 Q6PIU2 | Neutral cholesterol ester hydrolase 1 | NCEH1 AADACL1 KIAA1363 | −0.8525 | 0.0000 |
 Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | EIF4G1 EIF4F EIF4G EIF4GI | −0.8275 | 0.0275 |
 P06733 | Alpha-enolase | ENO1 ENO1L1 MBPB1 MPB1 | −0.7775 | 0.0000 |
 P11166 | Glucose transporter 1 | GLUT1 SLC2A1 | −0.7694 | 0.0006 |
 P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | USP14 TGT | −0.7558 | 0.0114 |
 P68363 | Tubulin alpha-1B chain | TUBA1B | −0.7398 | 0.0016 |
 P21980 | Protein-glutamine gamma-glutamyltransferase 2 | TGM2 | −0.5013 | 0.0003 |
 O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | PLOD2 | −0.4866 | 0.0003 |
 P35637 | RNA-binding protein FUS | FUS TLS | −0.3575 | 0.0449 |
 Q01082 | Spectrin beta chain, non-erythrocytic 1 | SPTBN1 SPTB2 | −0.2911 | 0.0260 |