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Fig. 5 | Cancer & Metabolism

Fig. 5

From: The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox

Fig. 5

Western blots for global histone H3 acetylation (H3Ac) and LaminB in MMTV-NEU-NT tumour and liver extracts. Tissues from treated mice (daily ip injection of 500 mg/kg β-OHB) and control mice were freeze-clamped at day 21. A representative blot is shown. Across the entire sample set, the mean (±se) intensity of global H3Ac relative to LaminB in treated tumours (n = 10) was 0.713 (±0.005) compared to 0.758 (±0.034) in the control tumours (n = 15), p = 0.22. In the treated livers, the mean intensity was 0.706 (n = 2) compared to 0.711 ± 0.002 (n = 4) in the control livers

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Cancer & Metabolism

ISSN: 2049-3002