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Fig. 4 | Cancer & Metabolism

Fig. 4

From: Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors

Fig. 4

Effect of CR on serum metabolomic profile. a Representative 1D 1H-MRS spectra of serum isolated from mice fed a control (n = 11) or CR (n = 11) diet for 20 weeks and transplanted with Atg5 +/+ cells. b Scores plots from principal component analysis (PCA) of 1H-MRS spectra from control and CR serum. c Differential metabolites identified in PCA between diet groups are indicated on 1H-MRS spectra

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