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Table 4 Fates of serine and glycine

From: Metabolic requirements for cancer cell proliferation

Biomass fate

Biosynthetic pathway

SHMT

GCS

Serine

0.65

–

Glycine

–

0.74

One carbon

0.35

0.26

  1. Values represent the fraction of total serine (or glycine) that must be metabolized through SHMT (or the GCS) to meet the demand for one-carbon units
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Cancer & Metabolism

ISSN: 2049-3002