Fig. 1
From: Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis
MID similarity analysis for pathway contextualization and detection of metabolically related compounds. a The pairwise similarities of all MIDs is determined. A similarity threshold is applied, and compounds with highly similar MIDs are visualized as network. Networks derived from different experimental conditions can be overlaid for more information. b Before the distance calculation the MID vectors are aligned to account for gains or losses of labeled fragments, which would otherwise conceal the metabolic proximity of these compounds