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Table 1 Differential expression of RWE-associated genes in GP3 versus GP4 stroma

From: Molecular characterization of Gleason patterns 3 and 4 prostate cancer using reverse Warburg effect-associated genes

Gene

p (Welch t)

p (MWU)

q

ROC (AUC)

Log2 (\(\overline {\mathrm {GP4}}/\overline {\mathrm {GP3}}\))

FOXO1

0.0008

0.0005

0.0495

0.884

–4.590

GPD2

0.0046

0.0034

–

0.707

–3.58

SPARC

0.0194

0.0119

–

0.769

3.12

HK2

0.0172

0.0132

–

0.752

–3.82

COL1A2

0.0191

0.0200

–

0.742

2.16

ALDOA

0.0118

0.0231

–

0.778

–2.60

SLC16A4

0.0392

0.0327

–

0.750

–3.43

NRF2

0.0197

0.0349

–

0.729

2.46

ATG5

0.0239

0.0410

–

0.748

–2.79

ACTA2

0.0255

0.1083

–

–

0.90

SIRT3

0.0375

0.1505

–

–

–3.25