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Fig. 2 | Cancer & Metabolism

Fig. 2

From: Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

Fig. 2

SCD expression is increased in breast and prostate cancers and associated with poor survival. a Differential expression of SCD between breast and prostate cancers and normal tissue found in different public datasets (Oncomine). b Immunohistochemical analysis of SCD in breast cancer and normal adjacent tissue (NAT) samples from invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC). SCD staining intensity was classified as absent, low or high. Representative images of NAT and IDC samples indicating staining intensities. c Correlation of SCD expression in IDC patient samples with tumour grade (Curtis dataset, Oncomine). d Kaplan Meier plots for relapse-free survival (RFS) stratified by SCD expression in breast cancers of different grades. e Kaplan Meier plots for RFS stratified by SCD expression in patients with basal-like breast cancers as determined by expression of the PAM50 signature

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Cancer & Metabolism

ISSN: 2049-3002