Fig. 1

Flux of hyperpolarized [1-¹³C] pyruvate to [1-¹³C] lactate in prostate regions. a MR image from patient with prostate cancer showing regions of cancerous tissue and surrounding normal tissue. b–d Localized dynamic hyperpolarized [1-¹³C]pyruvate and [1-¹³C]lactate spectral from voxels overlapping the contralateral region of prostate (turquoise), a region of prostate cancer (yellow), and a vessel outside the prostate (green). Adapted with permission from ref. [43]