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Fig. 4 | Cancer & Metabolism

Fig. 4

From: The rate of glycolysis quantitatively mediates specific histone acetylation sites

Fig. 4

The rate of glycolysis determines histone acetylation. a Western Blot of Pan-acetyl-H3 and H3K27ac in response to glucose titration with quantification, total H3 used as loading control. b Western Blot of Pan-acetyl-H3 and H3K27ac in response to 2DG treatment with quantification, total H3 used as loading control. c Scatter-plot depicting correlation between ac-CoA levels and H3K27ac levels. d Bar graph of Spearman correlation coefficient of ac-CoA:CoA, β-OHB, ac-acetate, ac-CoA, CoA, Pyr/Lac and NAD+. Mean ± SEM of triplicates (*P <0.05 versus Veh)

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