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Fig. 1 | Cancer & Metabolism

Fig. 1

From: The rate of glycolysis quantitatively mediates specific histone acetylation sites

Fig. 1

The rate of glucose metabolism and extent of metabolic reprogramming can be tuned with pharmacological manipulation. a Schematic of 2DG effect on glycolysis at high vs. low concentrations. b Relative extracellular glucose levels in response to each 2DG concentration compared to the vehicle (Veh). c Relative 2DG6P levels in response to 2DG treatment compared to Veh. d Production rate of 13C-labeled lactate in response to 2DG treatment. Fold change in relative amounts of lactate in media after respective treatments is depicted. e Cell viability test of HCT-116 cells after 6 h of growth under indicated treatments. Mean ± SEM of triplicates relative to the Veh. (*P < 0.05 relative to Veh)

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