Fig. 1From: The rate of glycolysis quantitatively mediates specific histone acetylation sitesThe rate of glucose metabolism and extent of metabolic reprogramming can be tuned with pharmacological manipulation. a Schematic of 2DG effect on glycolysis at high vs. low concentrations. b Relative extracellular glucose levels in response to each 2DG concentration compared to the vehicle (Veh). c Relative 2DG6P levels in response to 2DG treatment compared to Veh. d Production rate of 13C-labeled lactate in response to 2DG treatment. Fold change in relative amounts of lactate in media after respective treatments is depicted. e Cell viability test of HCT-116 cells after 6 h of growth under indicated treatments. Mean ± SEM of triplicates relative to the Veh. (*P < 0.05 relative to Veh)Back to article page