Fig. 1From: Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cellsSuppression of PDH E1α reduces abundance of metabolites downstream of PDH. a Western blot analysis for PDH E1α. Cyclophilin B was used as a loading control. b PDH activity from control cells and cells expressing PDHA1 shRNAs. c, d Intracellular levels of acetyl-carnitine and citrate. Values are the average and SD of biological triplicates, except (b) which represents technical triplicates. *P < 0.05; **P < 0.005Back to article page