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Figure 1 | Cancer & Metabolism

Figure 1

From: Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism

Figure 1

SDH components are downregulated in serous ovarian cancer. (A) Oncoprint depicting 575 patient samples with genetic loss of SDH subunits. Light blue and dark blue indicate heterozygous deletion and homozygous deletion, respectively. (B) A plot showing the relationship between SDHB mRNA abundance and copy number alteration of the SDHB gene. (C) Tumorscape copy number data for SDH subunits tabulated. Bold face indicates significance (q value < .01).

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Cancer & Metabolism

ISSN: 2049-3002