Figure 4
From: Endothelial cell metabolism: parallels and divergences with cancer cell metabolism
Endothelial versus cancer metabolism. Highlights of some common and distinct features of key metabolic pathways displayed by endothelial cells (A) and cancer cells (B). 1,3BPG 1,3-bisphosphoglyceric acid, 2PG 2-phosphoglycerate, 3PG 3-phosphoglycerate, Acetyl-CoA acetyl-coenzyme A, eNOS endothelial nitric oxide synthase, F1,6P 2 fructose 1,6 bisphosphate, F2,6P 2 fructose 2,6 bisphosphate, F6P fructose 6-phosphate, FA fatty acid, FABP fatty acid binding protein, FATP fatty acid transfer protein, G1P glucose 1-phosphate, G3P glyceraldehyde 3-phosphate, G6P glucose 6-phosphate, G6PD glucose-6-phosphate dehydrogenase, GAPDH glyceraldehyde 3-phosphate dehydrogenase, GFAT glutamine-fructose-6-phosphate transaminase, GlcN6P glucosamine-6-phosphate, GLDC glycine decarboxylase, GLS glutaminase, GLUT glucose transporter, Gly glycine, GS glutamine synthetase, NADP+/NADPH nicotinamide adenine dinucleotide phosphate, NO nitric oxide, OXPHOS oxidative phosphorylation, PC pyruvate carboxylase, PEP phosphoenolpyruvate, PFK phosphofructokinase, PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3, PGAM phosphoglycerate mutase, PHGDH phosphoglycerate dehydrogenase, PK pyruvate kinase, PPP pentose phosphate pathway, R5P ribose 5-phosphate, ROS reactive oxygen species, Ru5P ribulose 5-phosphate, SCO cytochrome c oxidase, Ser serine, TCA tricarboxylic acid, TKT transketolase, TKTL transketolase-like protein, UDP-GlcNAc uridine diphosphate N-acetylglucosamine, VEGFR2 vascular endothelial growth factor receptor 2.