|
Metabolite
|
Metabolite median fold change
|
P-value
|
|---|
|
Tigylglycine
|
3.4
|
0.0112
|
|
N-acetyl-glutamic acid
|
10
|
0.0331
|
|
Uridine monophosphate
|
2.0
|
0.0021
|
|
Isobutyrylcarnitine
|
2.3
|
0.0368
|
|
Stearic acid
|
4.7
|
0.0893
|
|
D-glucose
|
2.3
|
0.0713
|
- Raji cells were treated with Rapamycin or vehicle for 60 minutes as described in Materials and Methods, then divided into matching aliquots for NIMS analysis. Metabolites with unambiguous MS/MS fragmentation patterns that represent disparate metabolic pathways were also quantified and compared to reference standards via LC-MS/MS, and are shown here.
