Figure 6
From: Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
Glucose-6-phosphate dehydrogenase (G6PD) and p53 status are correlated in vivo . (A) Relative mRNA expression of GLS2 in the indicated cell lines under control or acidosis conditions. (B) Relative mRNA expression of G6PD in the indicated cell lines under control or acidosis conditions. (C,D) Relative NADP+/nicotinamide adenine dinucleotide phosphate (NADPH) ratio (C) and normalized ROS levels (D) in the indicated cell lines under control or acidosis conditions. (E) Relative expression level of G6PD mRNA in among groups of breast tumors with wild-type or mutant p53.