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Figure 5 | Cancer & Metabolism

Figure 5

From: Ets-1 global gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers

Figure 5

Breast cancer cell model of Ets-1 expression knockdown. MDA-MB-231 breast cancer cells were stably depleted of Ets-1 expression via targeted shRNA knockdown. (A) The Ets-1 knockdown cell line MDA-Ets1KD expresses Ets-1 protein at 22.7% of parental protein levels in MDA-MB-231 cells. (B) Real-time qRT-PCR of the breast cancer Ets-1 expression model. The gene expression of PDHA, CYC1, NDUFAB1 and SDHB were increased in MDA-Ets1KD cells, whereas the expression of G6PD was downregulated.

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Cancer & Metabolism

ISSN: 2049-3002