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Fig. 7 | Cancer & Metabolism

Fig. 7

From: Deficiency of TOP1MT enhances glycolysis through the stimulation of PDK4 expression in gastric cancer

Fig. 7

PDK4 was required for the upregulation of migration and lactate production in GC cells induced by TOP1MT silencing. A Western blot analysis for the detection of PDK4 expression in MGC-803 and HGC-27 cells. B The effects of M77976 on TOP1MT expression were analyzed by western blot. C Cell migration was assessed by transwell migration assays. D Representative experiments showing pH determination (BCECF-AM) after 48 h of culture in different groups. P values * < 0.05 and ** < 0.01

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Cancer & Metabolism

ISSN: 2049-3002