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Fig. 2 | Cancer & Metabolism

Fig. 2

From: Deficiency of TOP1MT enhances glycolysis through the stimulation of PDK4 expression in gastric cancer

Fig. 2

TOP1MT-related signaling pathway analysis. A The somatic landscape of a gastric cancer cohort. Genes are ordered by mutation frequency. B Lollipop charts of the mutated TOP1MT gene. C Cohort summary plot shows the distribution of variants according to variant classification, type and SNV class. D The volcano plot was constructed using the fold change values and P-adjust (TOP1MT-high vs. TOP1MT-low). E KEGG pathway enrichment and GO term enrichment results of differential genes. F The correlations between TOP1MT and glycolytic/gluconeogenesis pathway score were analyzed with Spearman

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Cancer & Metabolism

ISSN: 2049-3002