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Fig. 7 | Cancer & Metabolism

Fig. 7

From: Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages

Fig. 7

Autofluorescence imaging shows significant changes in cellular metabolism during macrophage activation after cytokine-stimulation. A) Representative optical redox (FAD/FAD+NADH) and mean NADH lifetime maps of M0 and M1 macrophages. Scale bars are 10 μm. B) Changes in optical redox ratios of M0 and M1 macrophages before and after cytokine stimulation. Changes in C) mean NADH lifetime (ns) and D) A1/A2 ratio over time. ** p ≤ 0.01; **** p ≤ 0.0001; Graphs were made in GraphPad Prism®

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