Fig. 5

Data summary of Seahorse XFp Cell Mito Stress Test. A Profiles of Mito Stress Test data for OCR and ECAR (n = 3, M0; n = 3, M1). Shaded regions indicate which complexes of the electron transport chain are affected due to modulators: Blue (Complex IV), Yellow (Proton Gradient), and Red (Rotenone: Complex 1 and Antimycin A: Complex III). B Energy phenotype profiles generated for M0 and M1 macrophages based on basal OCR and ECAR levels for all timepoints (1: 0 hours, 2: 24 hours, 3: 48 hours, and 4: 72 hours). * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001. Graphs were made in GraphPad Prism®