Fig. 6

Percentages of glycolytic and mitochondrial ATP production in untreated and treated H1975 and H1993 cells. A H1975 cells were treated for 48 h with 10-nM and 100-nM KU55933, 1-μM WZ4002, and a combination of 100-nM KU55933 with 0.5-μM WZ4002. B H1993 cells were treated for 48 h with 10-nM and 100-nM KU55933, 1-μM crizotinib, and a combination of 100-nM KU55933 with 0.5-μM crizotinib. Compared to untreated cells, the symbol ** indicates p < 0.01, whereas *** indicates p < 0.001