Fig. 2

Levels of extracellular glucose and intracellular metabolic intermediates in response to ATM inhibition. A Levels of residual glucose in culture media of H1993 and H1975 cells exposed to 10-nM and 100-nM of KU55933 for 48 h. Levels of intracellular B pyruvate, C citrate, and D succinate in H1993 and H1975 cells exposed to 100-nM of KU55933 for 48 h. Symbol * indicates a p-value < 0.05, symbol ** indicates a p-value < 0.01, symbol *** indicates a p-value < 0.001 versus NT