Fig. 2

MC-38 isograft tumor induction in ND-, HFD-, and HCD-fed C57BL/6 J mice. Mice fed on different diets were subcutaneously implanted with MC-38 cells. A Experimental setup for MC-38 tumor progression in the ND-, HFD-, and HCD-fed mice. In ND and HFD mice, B tumor progression. C Mice body weight recorded at the end of the experiment. D Serum cholesterol level during feeding of diets, i.e., before MC-38 isograft implantation. In ND and HCD mice, E tumor progression and F difference in body weight recorded before the termination of the experiment. G Serum cholesterol level measured during feeding of diets, i.e., before MC-38 isograft implantation