Fig. 1
From: Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells
AOM/DSS-induced colorectal carcinogenesis in ND-, HFD-, and HCD-fed C57BL/6J mice. Chemically induced colon cancer was developed by injecting AOM (10 mg/kg body weight) and followed by three cycles of DSS (2.5%) in drinking water as mentioned in the methods section. A Experimental design for AOM/DSS-induced colorectal carcinogenesis, In ND-, HFD-, and HCD-fed mice. B Body weight recorded at the end of the experiment. C Percentage of polyp’s occurrence. D Picture of colon-bearing polyps. E Differences in polyp’s diameter. F No. of polyps per colon in each group. G Colon length