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Fig. 1 | Cancer & Metabolism

Fig. 1

From: Restoring gluconeogenesis by TEF inhibited proliferation and promoted apoptosis and immune surveillance in kidney renal clear cell carcinoma

Fig. 1

Reprogram of glycolysis and gluconeogenesis was crucial for KIRC prognosis. A Volcano plot of DEGs in the comparison of KIRC vs NC. The color indicated the upregulated (red), downregulated (blue), nonsignificant (gray), and glycolysis/gluconeogenesis (green) genes in KIRC. B Heatmap of indicated glycolysis/gluconeogenesis genes in TCGA KIRC mRNA profile. The prognosis of each gene was annotated on the left side by the univariate Cox hazard analysis. C Boxplot of PGNG genes from paired TCGA KIRC patients and adjacent normal tissues. D Venn diagram of downregulated DEGs, protective genes, and glycolysis/gluconeogenesis genes. E KM plot of PGNG genes. The expression group was determined by median value of each gene. F Boxplot of ssGSEA score of PGNG in KIRC and adjacent normal tissues. G KM plot of ssGSEA score of PGNG. The group was determined by median value of ssGSEA score. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Cancer & Metabolism

ISSN: 2049-3002