Fig. 5

Levels of nucleotides after treatment with 3BP. The level of nucleotides following treatment with 3BP (100 μM) for 1 h (n = 6): (A) monophosphates, (B) di- and triphosphates, and (C) deoxyribonucleotides. The heatmaps show the statistical significance (P value < 0.05) of each metabolite change within each cell line. Gray squares in the heatmap indicate missing data. Error bars represent the standard deviation from the mean. *P < 0.05, **P < 0.01, ***P < 0.001. Asterisks indicate statistical significance of the difference between BT20 cells and each other cell type, unless otherwise shown. Statistical significance was calculated using two-way ANOVA, corrected for multiple comparisons by the Tukey test. The multiplicity adjusted P value is presented