Fig. 6
From: Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies
Oncogene expression and sensitivity to TOFA treatment in a limited panel of lymphoid cancer cell lines. A We obtained a panel of human lymphoma cells and calculated ED50 values (Supplemental Fig. 9A) and compared to measured relative MYC, RAS, and ABL1 expression levels (supplemental Fig. 10A). Median expression is indicated by dotted line. Cells resistant to TOFA treatment are indicated as greater than 30 μg/ml. MYC expression is associated TOFA sensitivity