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Fig. 7 | Cancer & Metabolism

Fig. 7

From: Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC

Fig. 7

Gene expression analysis of potential links between SDH suppression and EMT activation. Gene expression (mRNA) analysis correlating (Spearman) SDH subunits, EMT signature, TWIST1, and SNAI2 to panels of genes focusing on specific processes, based on data from the Affymetrix breast cancer patient meta cohort (n = 3992). The heat map panels reflect the directions and strength (Rho value) of the associations. The panels of genes included a HIF-1 targets, b factors involved in mitochondrial dynamic, c antioxidant enzymes, and d AMPK targets

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Cancer & Metabolism

ISSN: 2049-3002