Fig. 5
From: Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells
Both oxamate and GSK-2837808A significantly inhibit LDH activity in HeLa cell mitochondrial homogenates. a Mitochondria were first purified from HeLa cells and then homogenized before treating with oxamate (oxa) or GSK-2837808A (GSK). b LDH activity was measured by using a colorimetric assay. Both drugs significantly inhibited LDH activity compared to vehicle control. Data shown are averages from groups of n = 3. ***p < 0.001