Figure 2
From: The metabolic demands of cancer cells are coupled to their size and protein synthesis rates
Correlation between biomass components and doubling time or cell size. (a) Culture image of the relatively smaller colon cancer cell line HCT-116. (b) Culture image of the relatively larger renal cancer cell line A498. (c) The cell volume scales in proportion with the doubling time. The diamond and circle represent the HCT-116 and A498 cell lines, respectively. (d- f) The protein content, DNA content and protein synthesis rate scale in proportion to the cell volume. The blue dashed-dotted line in panel (e) represents the DNA content associated with the diploid genome of a normal cell. All other lines represent linear fits to the data points.