Follow up |  | Crude model †|  | Model 1  ‡ | Model 2 § | ||||
---|---|---|---|---|---|---|---|---|---|
 | HR (95% CI) | P |  | HR (95% CI) | P |  | HR (95% CI) | P | |
3-year | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  without interaction with statins with interaction with statins |  | 0.81 [0.74, 0.88] | < 0.001 |  | 0.83 [0.76, 0.90] | < 0.001 |  | 0.82 [0.75, 0.90] | < 0.001 |
    0 |  | - | - |  | 0.87 [0.79, 0.95] | 0.002 |  | 0.86 [0.78, 0.94] | 0.001 |
    1 |  | - | - |  | 0.84 [0.77, 0.92] | < 0.001 |  | 0.84 [0.76, 0.91] | < 0.001 |
    3 |  | - | - |  | 0.79 [0.73, 0.87] | < 0.001 |  | 0.79 [0.72, 0.86] | < 0.001 |
    5 |  | - | - |  | 0.75 [0.68, 0.83] | < 0.001 |  | 0.74 [0.67, 0.82] | < 0.001 |
5-year | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  without interaction with statins with interaction with statins¶ |  | 0.87 [0.83, 0.92] | < 0.001 |  | 0.88 [0.83, 0.93] | < 0.001 |  | 0.88 [0.83, 0.93] | < 0.001 |
    0 |  | - | - |  | 0.97 [0.90, 1.04] | 0.356 |  | 0.96 [0.89, 1.04] | 0.347 |
    1 |  | - | - |  | 0.94 [0.88, 1.00] | 0.047 |  | 0.94 [0.88, 1.00] | 0.050 |
    3 |  | - | - |  | 0.88 [0.84, 0.93] | < 0.001 |  | 0.88 [0.84, 0.93] | < 0.001 |
    5 |  | - | - |  | 0.83 [0.78, 0.89] | < 0.001 |  | 0.83 [0.78, 0.89] | < 0.001 |
7-year | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  without interaction with statins with interaction with statins¶ |  | 0.90 [0.85, 0.95] | < 0.001 |  | 0.90 [0.85, 0.96] | 0.001 |  | 0.91 [0.86, 0.97] | 0.002 |
    0 |  | - | - |  | 1.01 [0.92, 1.10] | 0.900 |  | 1.01 [0.93, 1.10] | 0.820 |
    1 |  | - | - |  | 0.98 [0.91, 1.05] | 0.517 |  | 0.98 [0.91, 1.06] | 0.617 |
    3 |  | - | - |  | 0.92 [0.87, 0.98] | 0.005 |  | 0.93 [0.87, 0.98] | 0.011 |
    5 |  | - | - |  | 0.87 [0.81, 0.92] | < 0.001 |  | 0.87 [0.82, 0.93] | < 0.001 |
10-year | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  without interaction with statins with interaction with statins |  | 0.95 [0.86, 1.05] | 0.325 |  | 0.95 [0.85, 1.05] | 0.283 |  | 0.96 [0.87, 1.06] | 0.437 |
    0 |  | - | - |  | 1.06 [0.94, 1.20] | 0.329 |  | 1.08 [0.95, 1.22] | 0.245 |
    1 |  | - | - |  | 1.03 [0.92, 1.16] | 0.588 |  | 1.05 [0.93, 1.17] | 0.445 |
    3 |  | - | - |  | 0.97 [0.88, 1.08] | 0.588 |  | 0.99 [0.89, 1.09] | 0.800 |
    5 |  | - | - |  | 0.92 [0.83, 1.01] | 0.086 |  | 0.93 [0.84, 1.03] | 0.163 |